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【买试剂,找华雅】ProteanFect®高分文献速览:11篇成果覆盖多种原代细胞,铸就免疫研究新标杆

ProteanFect® —— 作为全球首款基于内源蛋白凝聚体技术开发的转染试剂,正以前所未有的性能突破难转细胞壁垒。它不仅高效攻克了T、B、NK、HSC、iPSC及神经元等原代细胞,更在Jurkat、THP-1、K562等“血液系统难转细胞系”及各类实体瘤细胞中表现卓越。

ProteanFect®不仅支持mRNA、siRNA、DNA等多种核酸分子的常规基因功能研究,更深度适配RNP(核糖核蛋白)介导的基因编辑体系。凭借其优异的线性放大能力ProteanFect®能够满足从微量预实验到大规模验证的全流程,为学术研究提供稳健的底层技术支撑。

以下是近期发表的研究成果,展示了ProteanFect®在不同科研领域及细胞类型中的卓越表现:

题目:CD160 dictates anti-PD-1 immunotherapy resistance by regulating CD8+ T cell exhaustion in colorectal cancer

细胞:小鼠原代CD160? CD8? T细胞

目的:siRNA敲低基因

试剂盒:PT03

题目:Mycobacterium tuberculosis-derived linoleic acid increases regulatory T cell function to promote bacterial survival within macrophages

细胞:小鼠原代CD4+ Treg细胞

目的:siRNA敲低基因

试剂盒:PT03

题目:High fructose consumption aggravates inflammation by promoting effector T cell generation via inducing metabolic reprogramming

细胞:小鼠原代CD4+ T细胞

目的:Cas9 mRNA与sgRNA共转敲除基因

试剂盒:PT06


题目:H2A.Z primes an epigenetic landscape for memory CD8+ T cell recall response

细胞:人原代CD8? T细胞

目的:Cas9 mRNA与sgRNA共转敲除基因

试剂盒:PT05

题目:Spatially resolved multi-omics of human metabolic dysfunction-associated steatotic liver disease

细胞:THP1细胞

目的:siRNA敲低基因

试剂盒:PT01

题目:Phosphorylation of shiftless is important for inhibiting the programmed?1 ribosomal frameshift

细胞:Jurkat细胞

目的:质粒过表达基因

试剂盒:PT01

题目:Ginsenoside F3 alleviates T cell exhaustion via RIPOR2-mediated immunometabolic reprogramming to potentiate anti-PD-1 therapy

细胞:小鼠原代CD8+ T细胞

目的:siRNA敲低基因

试剂盒:PT03

 

题目:Single-nucleus RNA sequencing illuminates a functional analog of lymphoid organ in crustacean

细胞:Jurkat细胞

目的:质粒过表达基因

试剂盒:PT01

题目:Fatty acid uptake mediated by FABP4 promotes the formation of CD8+T cell senescence through lipid peroxidation in the adipocyte-rich microenvironment of Ovarian Cancer

细胞:小鼠原代CD8+ T细胞

目的:siRNA敲低基因

试剂盒:PT03

题目:Cord blood natural killer cell-derived extracellular vesicles inhibit Zika virus infectivity through ITGB2/perforin-mediated envelope disruption in vitro and in vivo

细胞:脐带血NK细胞

目的:siRNA敲低基因

试剂盒:PT02

 

题目:Single-round evolution of RNA aptamers with GRAPE-LM

细胞:Jurkat细胞

目的:spCas9-GFP蛋白与sgRNA共转敲除基因

试剂盒:PT08

ProteanFect®转染试剂盒,不仅是你攻克实验难关的得力工具,更已成为众多科研人发表高质量文献的“助推器”。

华雅思创生物作为西湖凝聚体的授权代理商,为您提供西湖凝聚体ProteanFect系列产品,欢迎联系华雅思创客服咨询购买