CHIR99021 (CT99021) is a glycogen synthase kinase 3β (GSK3β) inhibitor with IC50 less than 10 nM. Compared to other GSK-3 inhibitors, CHIR-99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) with 350-fold selectivity toward GSK-3β compared to CDKs .
Ref: Tighe A et al. BMC Cell Biol. 2007 Aug 14;8:34
Purity: Greater than 99% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: In a cell-based assay measuring the activation of the TCF reporter gene, this compound gives EC50 of 50 nM.
OriGen CP-70 CryoPur-DMSO 细胞冻存液 二甲基亚砜 进口USP级 CE认证 CP70￥960
Lifeline LL-0002 VascuLife EnGS Complete Kit 人内皮细胞培养基套装￥3,254
Anti-Human CD4 PerCP-Cyanine5.5 人CD4抗体￥4,188
CleanNA 核酸提取磁性微球 MYS300H￥880
Corning 88-571-kit Natural Killer Cell Serum-free Culture Kit II NK细胞活化扩增培养基套装￥0
Corning 88-600-CV Corning MSC xeno-free SFM Corning间充质干细胞无血清培养基￥3,571