Anti-CD3 mAb (GMP)
产品英文名称：Anti-CD3 mAb (GMP)
TAKARA CD3单克隆抗体（GMP）T210 产品介绍:
Anti-CD3 mAb (GMP)
The anti-CD3 monoclonal antibody (OKT3) recognizes CD3, a human glycoprotein and member of the Ig superfamily that is primarily expressed on T cells, some NKT cells, and thymocytes during T cell differentiation. Binding of an anti-CD3 monoclonal antibody to CD3 stimulates T cell activation. Anti-CD3 antibodies (the OKT3 clone in particular) are used to expand T cells in culture for use in adoptive immunotherapy. This product is manufactured as a quality-assured product according to guidelines for Good Manufacturing Practice (GMP) for Investigational Products, and is therefore suitable for ex vivo cell culture processing and gene therapy studies. T cell expansion can be further enhanced by co-stimulation with RetroNectin (GMP).
GMP-grade, animal-derived component free, anti-CD3 mouse monoclonal antibody.
Clinical grade Anti-CD3 mAb (GMP) can be used for ex vivo cell culture processing (investigational use only)—please complete and return this form prior to purchase.
Can be used in combination with RetroNectin (GMP) to enhance T cell expansion efficiency in culture.
Anti-CD3 antibodies are commonly used in T lymphocyte proliferation
protocols. Among many available clones, “OKT3” (mouse IgG2a) is the
most commonly used.
This monoclonal anti-CD3 antibody (clone OKT3) is manufactured as
a quality-assured product, according to relevant guidelines for Good
Manufacturing Practice (GMP). This product can be used for ex vivo cell
culture processing and is limited to investigational use only.
Mouse hybridoma cells
>95% by HPLC
Sterile solution in phosphate-buffered saline (PBS), pH7.4, with
200 ppm polysorbate 80.
1.0 mg protein/1.0 ml in a 2 ml cryovial
・ CIK (cytokine-induced killer) cell expansion by stimulation with
Anti-CD3 mAb (GMP) and cytokine.
・ T lymphocyte expansion by co-stimulation with Anti-CD3 mAb (GMP)
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