X-VIVO™ 15 Chemically Defined, Serum-free Hematopoietic Cell Medium
产品英文名称：X-VIVO™ 15 Chemically Defined, Serum-free Hematopoietic Cell Medium
X-VIVO™ Chemically Defined, Serum-free Hematopoietic Cell Medium 研究背景
Lonza’s R&D efforts and collaboration with many clinical trials have provided Lonza with the tools and expertise to support the developments in adoptive immunotherapy, cancer therapy, genetic therapy and other cellular therapies. Lonza’s philosophy for the development of serum-free formulations for use in cellular therapy is to provide a nutritionally complete and balanced environment for the cells. We have not included any exogenous growth factors, artificial stimulators of cellular proliferation or undefined supplements.
The products are devoid of any protein-kinase C stimulators and are suitable for the investigation of second messenger systems in the activation of human and murine lymphocytes. The formulations are complete and contain pharmaceutical grade human albumin, recombinant human insulin and pasteurized human transferrin. All X-VIVO™ Medium products are manufactured under current GMPs and are listed with the FDA in a product Master File. Permission to cross-reference the Master File may be obtained by contacting the Product Manager.
X-VIVO™ 15 Chemically Defined, Serum-free Hematopoietic Cell Medium 简介
X-VIVO™ 15 Medium is similar in composition to X-VIVO™ 10 Medium and has been optimized for the proliferation of Tumor Infiltrating Lymphocytes (TIL) under serum-free conditions. The formulation supports the proliferation of purified CD3+ cells isolated from peripheral blood and human tumors. X-VIVO™ 15 Medium has also been used to support the growth of human monocytes, macrophage cells and cell lines, PBL, granulocytes and natural killer (NK) cells. In addition, X-VIVO™ 15 Medium provides a serum-free environment for the expansion of HUT-78 and related human lymphocytic cell lines.
X-VIVO™ 15 化学成分确定的无血清造血细胞培养基特点
X-VIVO™ 15 Chemically Defined, Serum-free Hematopoietic Cell Medium 使用注意事项
1.X-VIVO™ 15 is similar in composition to X-VIVO™ 10 and has been optimized for the proliferation of Tumor Infiltrating Lymphocytes (TIL) under serum-free conditions.
2.Please see Supplemental Information for additional hematopoietic cell applications.
3.X-VIVO™ 15, catalog number 04-744Q contains L-glutamine but does not contain gentamicin or phenol red.
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