LDE225 (NVP-LDE225) is a potent antagonist of SMO (smoothened). This small molecule compound is a hedgehog pathway inhibitor by directly binding to SMO. This molecule has been developed by the Novartis Pharma for clinical application against hedgehog-dependent cancers.
• Purity: Greater than 99% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
• Biological Activity: In a cell-based assay measuring the activation of the Gli-1 reporter gene, this compound gives IC50 of 15-40 nM.
OriGen CP-70 CryoPur-DMSO 细胞冻存液 二甲基亚砜 进口USP级 CE认证 CP70￥960
Lifeline LL-0002 VascuLife EnGS Complete Kit 人内皮细胞培养基套装￥3,254
Anti-Human CD4 PerCP-Cyanine5.5 人CD4抗体￥4,188
CleanNA 核酸提取磁性微球 MYS300H￥880
Corning 88-571-kit Natural Killer Cell Serum-free Culture Kit II NK细胞活化扩增培养基套装￥0
Corning 88-600-CV Corning MSC xeno-free SFM Corning间充质干细胞无血清培养基￥3,571